What is immune adsorption?
Immune adsorption is a therapy which uses adsorbing materials to alternatively or specifically remove the pathogenic factors related to immune system in the blood. It usually used in immune system diseases and liver diseases.
What are the functions of immune adsorption?
- Removes the large-molecule toxins in the blood, such as immunoglobulin, immune complexes, albumin, endotoxin, cytokines and Inflammatory mediators.
- Remove the antibody from antiserum by use of specific antigen.
- Remove antigen by specific antiserum in a similar manner.
- It is the excessive antigens, antibodies or immune complexes that cause the endless damages to kidneys. Thereby, immune adsorption helps stop the development of kidney disease very soon.
What are the features of immune adsorption?
- It deals with the large size wastes in the blood
- It helps control the inflammatory factors generation and spread and slow down the development of medical condition.
- It is very useful in immune system disease, especially allergic immune kidney disease for it can remove the allergic toxins in the blood.
- It usually is used together with Plasma Exchange.
- Its indications include IgA Nephropathy, crescentic Glomerulonephritis, empsyxis caused by nephritis syndrome, lupus nephritis, cancer complicated with Hemolytic Uremic Syndrome, blood diseases, Purpura, rheumatoid arthritis, chronic allograft nephropathy.
What types of immune adsorption are there?
There are two types of immune adsorption, including plasma immune adsorption (TR-350L,PH-350L,BR-350L) and DNA immune adsorption.
Dos and donts of immune adsorption
- increase protein intake decrease potassium, phosphate intake and limit fluids.
- avoid morphine codeine; reduce doses of SSRIs and avoid vitamin A supplements.
- Monitor potassium levels
- Control BP and lipid levels
- Keep immunizations up to date, particularly in patients who may be candidates for transplantation
- Assess patient for anxiety
- Testing for renal osteodystrophy and follow-up if results abnormal.
- Smoking and alcohol cessation
- Maintenance of healthy weight
- Regular excise